Tuning the cell-cell distance via the non-signaling extracellular spacer domain of chimeric antigen receptors is critical for optimal activity

Cancer Cell

Building smart CAR T cell therapies: The path to overcome current challenges

American Society for Gene & Cell Therapy (ASGCT)

OutSmart™ IL-2/15 Safely Stimulates CAR T Proliferation and Persistence in the Tumor while Limiting Regulatory T Cell Activation